Bioinformatics Software (listed in alphabetical order)
| Name | Application purpose | Links | Program type | Module name | Server |
|---|---|---|---|---|---|
| ABySS | NGS, assembly | publication, tutorial | command line tool | ABYSS | gwdu100, HPC |
| parallel assembler for short read sequence data | |||||
| ALLPATHS-LG | NGS, assembly | homepage, tutorial | command line tool | ALLPATHSLG | gwdu100, HPC |
| short read genome assembler | |||||
| AMOS | NGS, assembly | publication, tutorial | command line tool | AMOS | gwdu100, HPC |
| modular open source whole genome assembler | |||||
| AUGUSTUS | gene prediction, genomics | homepage | command line tool | AUGUSTUS | gwdu100, HPC |
| gene prediction program for eukaryotes | |||||
| BamTools | NGS, sequence alignment | tutorial | command line tool | BAMTOOLS | gwdu100, HPC |
| command-line toolkit for for handling genome alignment files | |||||
| BBMap | NGS, sequence alignment | homepage, tutorial | command line tool | BBMAP | gwdu100, HPC |
| a splice-aware global aligner for DNA and RNA sequencing reads | |||||
| BCFtools | NGS, utilities, variants | homepage, tutorial | command line tool | BCFTOOLS | gwdu100, HPC |
| utilities for variant calling and manipulating VCFs and BCFs | |||||
| bcl2fastq | NGS, utilities | homepage | command line tool | BCL2FASTQ | gwdu100, HPC |
| demultiplexes data and converts BCL files generated by Illumina sequencing systems to standard FASTQ file formats | |||||
| Beagle | analysis, genomics | homepage | command line tool | BEAGLE | gwdu100, HPC |
| software package for analysis of large-scale genetic data sets | |||||
| BEAST | phylogenetics | homepage | command line tool | BEAST | gwdu100, HPC |
| Software package for phylogenetic analysis with an emphasis on time-scaled trees. | |||||
| Beast2 | phylogenetics | homepage | command line tool | BEAST2 | gwdu100, HPC |
| Bayesian Evolutionary Analysis by Sampling Trees (rewrite of BEAST) | |||||
| bedtools | genomics, utilities | homepage, tutorial | command line tool | BEDTOOLS | Galaxy, gwdu100, HPC |
| toolset for genome arithmetic | |||||
| BESST | NGS, scaffolding | publication, tutorial | command line tool | BESST | gwdu100, HPC |
| scaffolding of large fragmented assemblies | |||||
| BinPacker | NGS, assembly | publication | command line tool | BINPACKER | HPC |
| packing-based de novo transcriptome assembly from RNA-seq data | |||||
| BioPerl | toolkit | homepage | command line tool | BIOPERL | gwdu100, HPC |
| open source bioinformatics toolkit for writing bioinformatics scripts | |||||
| biotools | utilities | homepage | command line tool | BIOTOOLS | gwdu100, HPC |
| Python package of bioinformatics utilities | |||||
| Bowtie 1 | NGS, sequence alignment | homepage | command line tool | BOWTIE1 | Galaxy, gwdu100, HPC |
| ultrafast, memory-efficient short read aligner | |||||
| Bowtie 2 | NGS, sequence alignment | homepage | command line tool | BOWTIE2 | Galaxy, gwdu100, HPC |
| ultrafast and memory-efficient tool for aligning sequencing reads to long reference sequences | |||||
| Bracken | metagenomics | homepage | command line tool | BRACKEN | gwdu100, HPC |
| A highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. Braken uses taxonomy labels assigned by Kraken/Kraken2. | |||||
| BUSCO | NGS, quality control, special purpose | homepage, publication | command line tool | BUSCO | gwdu100, HPC |
| quantitative measures for the assessment of genome assembly, gene set, and transcriptome completeness | |||||
| BUSTER | structural biology | homepage, tutorial | command line tool | BUSTER | gwdu100, HPC |
| crystallographic structure refinement using Bayesian statistical methods | |||||
| Burrows-Wheeler Aligner | NGS, sequence alignment | homepage | command line tool | BWA | Galaxy, gwdu100, HPC |
| software package for mapping low-divergent sequences against a large reference genome | |||||
| Canu | NGS, assembly, nanopore sequencing | documentation | command line tool | CANU | gwdu100, HPC |
| Canu is a fork of the Celera Assembler designed for high-noise single-molecule sequencing (such as the PacBio RSII or Oxford Nanopore MinION). | |||||
| CEAS | genomics, special purpose | homepage | command line tool | CEAS | gwdu100, HPC |
| Cis-regulatory Element Annotation System for characterization of genome-wide protein-DNA interaction patterns from ChIP | |||||
| Celera Assembler | NGS, assembly | homepage | command line tool | CELERA_ASSEMBLER | gwdu100, HPC |
| de novo whole-genome shotgun (WGS) DNA sequence assembler | |||||
| Cell Ranger | NGS, sequence alignment, single cell analysis | homepage | command line tool | CELL_RANGER | gwdu100, HPC |
| A set of analysis pipelines that process Chromium single cell 3' RNA-seq output to align reads, generate gene-cell matrices and perform clustering and gene expression analysis. For viewer software, see Loupe Cell Browser. | |||||
| Cicero | NGS, single cell analysis | homepage | command line tool | CICERO | gwdu100, HPC |
| Cicero is an R package that provides tools for analyzing single-cell chromatin accessibility experiments. | |||||
| Circos | visualization | homepage | command line tool | CIRCOS | gwdu100, HPC |
| software package for visualizing data and information in a circular layout | |||||
| Clustal W | multiple sequence alignment, sequence alignment | homepage, tutorial | command line tool | CLUSTALW | gwdu100, HPC |
| command-line tool for multiple alignment of nucleic acid and protein sequences | |||||
| Clustal X | multiple sequence alignment, sequence alignment | homepage, tutorial | graphical user interface | CLUSTALX | gwdu100, HPC |
| version of Clustal W with a GUI | |||||
| CNVnator | genomics, special purpose | publication, tutorial | command line tool | CNVNATOR | gwdu100, HPC |
| a tool for CNV discovery and genotyping from depth-of-coverage by mapped reads | |||||
| ctffind | electron microscopy | homepage | command line tool | CTFFIND | gwdu100, HPC |
| program for finding CTFs of electron micrographs | |||||
| Cufflinks | NGS, analysis, assembly | homepage | command line tool | CUFFLINKS | gwdu100, HPC |
| assembles transcripts, estimates their abundances, and tests for differential expression and regulation in RNA-Seq samples | |||||
| Cutadapt | NGS, filter/trimming | publication, tutorial | command line tool | CUTADAPT | gwdu100, HPC |
| searches for the adapter in all reads and removes it when found | |||||
| deepTools | NGS, analysis | homepage | command line tool | DEEPTOOLS | Galaxy, gwdu100, HPC |
| command-line tools to process and analyze deep sequencing data | |||||
| DELLY2 | analysis, genomics, variants | publication, tutorial | command line tool | DELLY2 | gwdu100, HPC |
| structural variant discovery by integrated paired-end and split-read analysis | |||||
| DESeq | NGS, analysis | publication, homepage | command line tool | DESEQ | Galaxy, gwdu100, HPC |
| differential gene expression of RNA-seq data at the gene level | |||||
| DETONATE | NGS, assembly | homepage | command line tool | DETONATE | gwdu100, HPC |
| de novo transcriptome RNA-seq assembly | |||||
| DEXSeq | NGS, special purpose | publication, homepage | command line tool | DEXSEQ | gwdu100, HPC |
| package for finding differential exon usage using RNA-seq exon counts | |||||
| DIALS | structural biology | homepage | command line tool | DIALS | HPC |
| diffraction integration software for X-ray crystallography | |||||
| Entrez Direct | utilities | homepage | command line tool | EDIRECT | gwdu100, HPC |
| Entrez Direct (EDirect) provides access to the NCBI's suite of interconnected databases (publication, sequence, structure, gene, variation, expression, etc.) from a UNIX terminal window. | |||||
| EMBOSS | analysis, toolkit | homepage, tutorial | command line tool | EMBOSS | Galaxy, gwdu100, HPC |
| analysis package for molecular biology (all programs are listed by command 'wossname', a detailed program description is displayed by 'tfm program_name') | |||||
| exomePeak | NGS, analysis | publication, homepage | command line tool | EXOMEPEAK | gwdu100, HPC |
| exome-based analysis for RNA epigenome sequencing data | |||||
| Exonerate | sequence alignment | homepage | command line tool | EXONERATE | gwdu100, HPC |
| sequence alignment tool for pairwise sequence comparison | |||||
| eXpress | NGS, special purpose | homepage | command line tool | EXPRESS | gwdu100, HPC |
| streaming fragment assignment and quantification for high-throughput sequencing | |||||
| FASTA | sequence alignment | homepage | command line tool | FASTA | gwdu100, HPC |
| sequence comparison | |||||
| FastQC | NGS, quality control | homepage | command line tool | FASTQC | Galaxy, gwdu100, HPC |
| quality control tool for high throughput sequence data | |||||
| fastStructure | NGS, phylogenetics | homepage, publication | command line tool | FASTSTRUCTURE | gwdu100, HPC |
| A variational framework for inferring population structure from SNP genotype data. | |||||
| FASTX | NGS, toolkit | homepage | command line tool | FASTX | gwdu100, HPC |
| collection of command line tools for Short-Reads FASTA/FASTQ files preprocessing | |||||
| Filtlong | NGS, filter/trimming | homepage | command line tool | FILTLONG | gwdu100, HPC |
| Filtlong is a tool for filtering long reads by quality. | |||||
| FitHiChIP | Hi-C, NGS | homepage, publication | command line tool | FITHICHIP | gwdu100, HPC |
| Statistically Significant loops from HiChIP data | |||||
| Flappie | NGS, nanopore sequencing | homepage | command line tool | FLAPPIE | gwdu100, HPC |
| Flip-flop basecaller for Oxford Nanopore reads. | |||||
| Flye | NGS, assembly, nanopore sequencing | homepage | command line tool | FLYE | gwdu100, HPC |
| Flye is a de novo assembler for single molecule sequencing reads. | |||||
| freebayes | SNP, variants | homepage | command line tool | FREEBAYES | gwdu100, HPC |
| Bayesian haplotype-based genetic polymorphism discovery and genotyping. | |||||
| GapFiller | NGS, scaffolding | publication | command line tool | GAPFILLER | gwdu100, HPC |
| stand-alone program for closing gaps within pre-assembled scaffolds | |||||
| GATK | NGS, variants | homepage | command line tool | GATK | gwdu100, HPC |
| toolkit for variant discovery in high-throughput sequencing data | |||||
| Geneious | NGS, analysis, assembly, molecular biology, sequence alignment, special purpose, visualization | homepage | graphical user interface | GENEIOUS | gwdu100 |
| a powerful and comprehensive suite of molecular biology and NGS analysis tools with very good visualization | |||||
| GenomeTools | analysis, genomics | homepage | command line tool | GENOMETOOLS | gwdu100, HPC |
| bioinformatics tools for genome analysis | |||||
| GMAP/GSNAP | sequence alignment | homepage | command line tool | GMAP | gwdu100, HPC |
| GMAP: Genomic Mapping and Alignment Program for mRNA and EST Sequences. GSNAP: Genomic Short-read Nucleotide Alignment Program | |||||
| Gromacs | structural biology | homepage | command line tool | GROMACS | HPC |
| a versatile package to perform molecular dynamics, i.e. simulate the Newtonian equations of motion for systems with hundreds to millions of particles | |||||
| Guppy | NGS, nanopore sequencing | homepage | command line tool | GUPPY | gwdu100, HPC |
| Accelerated basecaller for Oxford Nanopore Sequencing | |||||
| Hail | NGS, analysis, annotation, quality control, toolkit, visualization | homepage | command line tool | HAIL | HPC |
| Hail is an open-source, scalable framework for exploring and analyzing genomic data. | |||||
| HMMER | sequence alignment, special purpose | homepage | command line tool | HMMER | gwdu100, HPC |
| biosequence analysis using profile hidden Markov models | |||||
| HiC-Pro | Hi-C, NGS, visualization | documentation, publication | command line tool | HIC-PRO | gwdu100, HPC |
| HiC-Pro: An optimized and flexible pipeline for Hi-C data processing | |||||
| hichipper | Hi-C, NGS, quality control | homepage, documentation | command line tool | HICHIPPER | gwdu100, HPC |
| hichipper is a command-line toolkit that performs restriction fragment bias-aware preprocessing of HiChIP data. | |||||
| HISAT2 | NGS, sequence alignment | homepage | command line tool | HISAT2 | Galaxy, gwdu100, HPC |
| A fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). | |||||
| HOMER | NGS, analysis, toolkit | homepage | command line tool | HOMER | gwdu100, HPC |
| suite of tools for Motif Discovery and next generation sequencing analysis | |||||
| HTSeq | NGS, utilities | publication, homepage | command line tool | HTSEQ | Galaxy, gwdu100, HPC |
| Python package that provides infrastructure to process data from high-throughput sequencing assays | |||||
| IDBA | NGS, assembly | homepage | command line tool | IDBA | gwdu100, HPC |
| de novo assembler for short reads sequencing data with highly uneven sequencing depths | |||||
| Integrative Genomics Viewer | genome browser, genomics, visualization | homepage, publication | graphical user interface | IGV | gwdu100, HPC |
| high-performance visualization tool for genomic datasets | |||||
| iMOSFLM | structural biology | homepage | graphical user interface | iMOSFLM | HPC |
| a program for integrating single crystal diffraction data from area detectors | |||||
| InterProScan | analysis, protein, special purpose | homepage, publication | command line tool | INTERPROSCAN | gwdu100, HPC |
| protein sequence search | |||||
| ipyrad | NGS, RADseq, analysis, assembly | documentation | command line tool | IPYRAD | gwdu100, HPC |
| interactive assembly and analysis of RADseq data sets | |||||
| Jellyfish | utilities | homepage, tutorial | command line tool | JELLYFISH | gwdu100, HPC |
| A tool for fast, memory-efficient counting of k-mers in DNA | |||||
| JMP Genomics | NGS, genomics, visualization | homepage | graphical user interface | GWD-WinTSBio | |
| advanced genomic data analysis software with very good visualization (part of the SAS-JMP-bundle) | |||||
| kallisto | NGS, analysis | homepage, publication | command line tool | KALLISTO | gwdu100, HPC |
| program for quantifying abundances of transcripts from RNA-Seq data | |||||
| Katuali | NGS, analysis, nanopore sequencing | homepage, documentation | command line tool | KATUALI | gwdu100, HPC |
| Katuali is a flexible consensus pipeline implemented in Snakemake to basecall, assemble, and polish Oxford Nanopore Technologies' sequencing data. | |||||
| KisSplice | NGS, assembly | homepage | command line tool | KISSPLICE | gwdu100, HPC |
| local transcriptome assembler for SNPs, indels and AS events | |||||
| KNIME | utilities | homepage | graphical user interface | KNIME | gwdu100 |
| more than 1500 modules, hundreds of ready-to-run examples, community contributions, and tool integrations | |||||
| Kraken2 | classification, metagenomics | homepage | command line tool | KRAKEN2 | gwdu100, HPC |
| A taxonomic classification system using exact k-mer matches to achieve high accuracy and fast classification speeds. The assisting tool Bracken is available in a separate module. | |||||
| kSNP | SNP, phylogenetics, variants | homepage | command line tool | KSNP | gwdu100, HPC |
| kSNP identifies the pan-genome SNPs in a set of genome sequences, and estimates phylogenetic trees based upon those SNPs. | |||||
| LoRDEC | NGS, quality control | homepage | command line tool | LORDEC | gwdu100, HPC |
| LoRDEC is a program to correct sequencing errors in long reads from 3rd generation sequencing with high error rate, and is especially intended for PacBio reads. | |||||
| Loupe Cell Browser | NGS, analysis, visualization | homepage | graphical user interface | GWD-WinTSBio | |
| A desktop application for Windows and MacOS that allows you to quickly and easily visualize and analyze 10x Chromium Single Cell 5' and 3' gene expression data. | |||||
| MACS2 | ChIP-Seq, NGS, analysis | homepage | command line tool | MACS2 | Galaxy, gwdu100, HPC |
| Model-based Analysis of ChIP-Seq data for identifying transcript factor binding sites | |||||
| MAFFT | multiple sequence alignment, sequence alignment | homepage, publication | command line tool | MAFFT | gwdu100, HPC |
| multiple alignment program for amino acid or nucleotide sequences | |||||
| MAKER | annotation, genomics | homepage, publication | command line tool | MAKER | gwdu100, HPC |
| genome annotation pipeline | |||||
| MarkerMiner | NGS, analysis, phylogenetics | homepage, publication | command line tool | MARKERMINER | gwdu100, HPC |
| fully automated workflow and application for discovery of SCN loci in angiosperms | |||||
| MARVEL | NGS, assembly, nanopore sequencing | homepage | command line tool | MARVEL | gwdu100, HPC |
| MARVEL consists of a set of tools that facilitate the overlapping, patching, correction and assembly of noisy (not so noisy ones as well) long reads. | |||||
| Mauve | multiple sequence alignment, sequence alignment | homepage, publication | graphical user interface | MAUVE | Galaxy, gwdu100, HPC |
| Mauve is a system for constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion. | |||||
| Medaka | NGS, nanopore sequencing | homepage, documentation | command line tool | MEDAKA | gwdu100, HPC |
| Medaka is a tool to create a consensus sequence from nanopore sequencing data. | |||||
| MEME | analysis, special purpose, toolkit | homepage | command line tool | MEME | Galaxy, gwdu100, HPC |
| supports motif-based analysis of DNA, RNA and protein sequences | |||||
| Miniasm | NGS, assembly, nanopore sequencing | homepage | command line tool | MINIASM | gwdu100, HPC |
| Ultrafast de novo assembly for long noisy reads (though having no consensus step) | |||||
| Minimap2 | NGS, nanopore sequencing, sequence alignment | homepage, publication, manual | command line tool | MINIMAP2 | gwdu100, HPC |
| A versatile pairwise aligner for genomic and spliced nucleotide sequences | |||||
| MIRA | NGS, assembly | homepage | command line tool | MIRA | gwdu100, HPC |
| a multi-pass DNA sequence data assembler/mapper for whole genome and EST/RNA-seq projects | |||||
| miRDeep2 | NGS, analysis, special purpose | documentation, publication, tutorial | command line tool | MIRDEEP2 | gwdu100, HPC |
| A tool for discovering known and novel miRNAs from small RNA sequencing data. | |||||
| miRExpress | NGS, analysis, special purpose | homepage, publication | command line tool | MIREXPRESS | gwdu100, HPC |
| tool to analyze high-throughput sequencing data for profiling microRNA expression | |||||
| Miropeats | visualization | homepage | command line tool | MIROPEATS | gwdu100, HPC |
| Miropeats discovers regions of sequence similarity amongst any set of DNA sequences and presents this similarity information graphically. | |||||
| mirPRo | NGS, analysis, special purpose | homepage, publication | command line tool | MIRPRO | gwdu100, HPC |
| a novel standalone program for differential expression and variation analysis of miRNAs | |||||
| Monocle3 | single cell analysis | homepage | command line tool | MONOCLE3 | gwdu100, HPC |
| Monocle 3 is an analysis toolkit for single-cell RNA-Seq experiments. | |||||
| mothur | microbial ecology | homepage | command line tool | MOTHUR | gwdu100, HPC |
| open-source expandable software for the bioinformatic needs of microbial ecology | |||||
| MOTHUR-GUI | microbial ecology | homepage | graphical user interface | MOTHUR-GUI | gwdu100, HPC |
| Gui version of mothur | |||||
| MrBayes | phylogenetics | homepage | command line tool | MRBAYES | gwdu100, HPC |
| program for Bayesian inference and model choice across a wide range of phylogenetic and evolutionary models | |||||
| MUMmer | sequence alignment | homepage | command line tool | MUMMER | gwdu100, HPC |
| a system for rapidly aligning entire genomes | |||||
| MUSCLE | multiple sequence alignment | homepage, publication | command line tool | MUSCLE | gwdu100, HPC |
| multiple sequence alignment | |||||
| Nanofilt | NGS, filter/trimming, nanopore sequencing | homepage, publication | command line tool | NANOFILT | gwdu100, HPC |
| Filtering and trimming of long read sequencing data | |||||
| Nanopolish | NGS, assembly, nanopore sequencing | manual | command line tool | NANOPOLISH | gwdu100, HPC |
| Software package for signal-level analysis of Oxford Nanopore sequencing data | |||||
| NanoStat | NGS, nanopore sequencing | homepage, publication | command line tool | NANOSTAT | gwdu100, HPC |
| Create statistic summary of an Oxford Nanopore read dataset | |||||
| NCBI-BLAST | classification, sequence alignment | homepage | command line tool | NCBI-BLAST | Galaxy, gwdu100, HPC |
| basic local alignment search tool | |||||
| NCBI-TOOLS | NGS, toolkit | homepage | command line tool | NCBI-TOOLS | gwdu100, HPC |
| more than 700 tools, e.g. for downloading custom data sets | |||||
| ngs.plot | NGS, visualization | publication | command line tool | NGSPLOT | gwdu100, HPC |
| a standalone program to visualize enrichment patterns of DNA-interacting proteins at functionally important regions based on NGS data. | |||||
| Oases | NGS, assembly | homepage, publication | command line tool | OASES | gwdu100, HPC |
| de novo transciptome assembler for very short reads | |||||
| PartitionFinder | phylogenetics | homepage | command line tool | PARTITIONFINDER | gwdu100, HPC |
| select best-fit partitioning schemes and models of molecular evolution for phylogenetic analyses | |||||
| Pauvre | NGS, genome browser, nanopore sequencing | homepage | command line tool | PAUVRE | HPC |
| QC and genome browser plotting Oxford Nanopore and PacBio long reads | |||||
| PGURE-SVT | microscopy | homepage, publication | command line tool | PGURESVT | gwdu100, HPC |
| algorithm for denoising time-resolved microscopy image sequences | |||||
| phASER | special purpose | homepage, publication | command line tool | PHASER | gwdu100, HPC |
| phasing and Allele Specific Expression from RNA-seq | |||||
| PHYLIP | phylogenetics | homepage | command line tool | PHYLIP | gwdu100, HPC |
| PHYLogeny Inference Package: programs for inferring phylogenies | |||||
| PhyML | phylogenetics | homepage | command line tool | PHYML | Galaxy, gwdu100, HPC |
| Phylogenetic estimation using (Maximum) Likelihood | |||||
| Picard | NGS | homepage | command line tool | PICARD | Galaxy, gwdu100, HPC |
| set of command line tools for manipulating high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF | |||||
| Pilon | NGS, assembly, variants | homepage | command line tool | PILON | gwdu100, HPC |
| Pilon is an automated genome assembly improvement and variant detection tool. | |||||
| Platanus | NGS, assembly | homepage, publication | command line tool | PLATANUS | gwdu100, HPC |
| PLATform for Assembling NUcleotide Sequences is a novel de novo sequence assembler that can reconstruct genomic sequences of highly heterozygous diploids from massively parallel shotgun sequencing data | |||||
| PLINK | analysis, genomics, toolkit | homepage | command line tool | PLINK | gwdu100, HPC |
| whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner | |||||
| POPBAM | NGS, phylogenetics | publication | command line tool | POPBAM | gwdu100, HPC |
| tools for evolutionary analysis of short read sequence alignments | |||||
| Pomoxis | NGS, analysis, nanopore sequencing | documentation | command line tool | POMOXIS | gwdu100, HPC |
| Pomoxis comprises a set of basic bioinformatic tools tailored to nanopore sequencing. | |||||
| Porechop | NGS, filter/trimming, nanopore sequencing | homepage | command line tool | PORECHOP | HPC |
| adapter trimmer for Oxford Nanopore reads | |||||
| poretools | NGS, nanopore sequencing, toolkit | homepage | command line tool | PORETOOLS | gwdu100, HPC |
| toolkit for working with nanopore sequencing data from Oxford Nanopore | |||||
| PROFphd | protein, structural biology | homepage | command line tool | PROFPHD | gwdu100, HPC |
| Predicts protein secondary structure using a system of neural networks | |||||
| Proteome Discoverer | protein | homepage | graphical user interface | GWD-WinTSBio | |
| only usable as viewer on our server | |||||
| pyRAD | NGS, RADseq, assembly, phylogenetics | publication | command line tool | PYRAD | gwdu100, HPC |
| assembly of de novo RADseq loci for phylogenetic analyses | |||||
| QUAST | NGS, quality control | homepage, manual | command line tool | QUAST | gwdu100, HPC |
| QUAST stands for QUality ASsessment Tool. The tool evaluates genome assemblies by computing various metrics. | |||||
| Racon | NGS, assembly | publication, tutorial | command line tool | RACON | gwdu100, HPC |
| ultrafast consensus module for raw de novo genome assembly of long uncorrected reads | |||||
| RAxML | phylogenetics | homepage | command line tool | RAXML | gwdu100, HPC |
| Randomized Axelerated Maximum Likelihood: tool for maximum-likelihood based phylogenetic inference | |||||
| RAxML Next Generation | phylogenetics | documentation, publication | command line tool | RAXML-NG | gwdu100, HPC |
| A phylogenetic tree inference tool which uses maximum-likelihood (ML) optimality criterion. | |||||
| RECON | genomics, special purpose | homepage, publication | command line tool | RECON | gwdu100, HPC |
| program for prediction of nucleosome formation potential | |||||
| RELION | electron microscopy | tutorial | graphical user interface | RELION | gwdu100, HPC |
| REgularised LIkelihood OptimisatioN: a program for an empirical Bayesian approach to refinement of (multiple) 3D reconstructions or 2D class averages in electron cryo-microscopy | |||||
| RepeatMasker | genomics, special purpose | homepage | command line tool | REPEATMASKER | gwdu100, HPC |
| program that screens DNA sequences for interspersed repeats and low complexity DNA sequences | |||||
| Rgui | statistics | homepage | graphical user interface | GWD-WinTSBio | |
| graphical user interface for R | |||||
| Rosetta | protein, structural biology | homepage | command line tool | ROSETTA | HPC |
| software suite including algorithms for computational modeling and analysis of protein structures | |||||
| RSEM | NGS, analysis | publication | command line tool | RSEM | gwdu100, HPC |
| accurate transcript quantification from RNA-Seq data with or without a reference genome | |||||
| RSeQC | NGS, quality control | homepage | command line tool | RSEQC | gwdu100, HPC |
| a package that provides a number of useful modules that can comprehensively evaluate high throughput sequence data especially RNA-seq data | |||||
| Rstudio | statistics | homepage | graphical user interface | GWD-WinTSBio | |
| A free and open-source environment for R, a programming language for statistical computing. Also available as RStudio-Server. | |||||
| Salmon | NGS, analysis | homepage | command line tool | SALMON | gwdu100, HPC |
| A tool for quantifying the expression of transcripts using RNA-seq data. | |||||
| Samtools | NGS, sequence alignment, utilities | homepage | command line tool | SAMTOOLS | Galaxy, gwdu100, HPC |
| various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format | |||||
| Scallop | NGS, assembly | homepage, publication | command line tool | SCALLOP | HPC |
| Scallop is a reference-based transcriptome assembler for RNA-seq. | |||||
| Scrappie | NGS, nanopore sequencing | homepage | command line tool | SCRAPPIE | HPC |
| Basecaller for Oxford Nanopore Sequencing | |||||
| Shasta | NGS, nanopore sequencing | documentation | command line tool | SHASTA | gwdu100, HPC |
| De novo assembly from Oxford Nanopore reads. | |||||
| SignalP | protein, special purpose | homepage, publication | command line tool | SIGNALP | gwdu100, HPC |
| prediction of presence and location of signal peptide cleavage sites in amino acid sequences | |||||
| simRRLs | phylogenetics, special purpose | homepage | command line tool | SIMRRLS | gwdu100, HPC |
| simulation of raw restriction-site associated DNA fastq files for testing assembly methods on raw data | |||||
| SINA | multiple sequence alignment, sequence alignment | homepage, publication | command line tool | SINA | gwdu100, HPC |
| tool for aligning sequences with an existing multiple sequence alignment (MSA) at high accuracy | |||||
| SMARTdenovo | NGS, assembly, nanopore sequencing | homepage | command line tool | SMARTDENOVO | gwdu100, HPC |
| Ultra-fast de novo assembler using long noisy reads. | |||||
| SNAP | gene prediction, genomics | homepage | command line tool | SNAP | gwdu100, HPC |
| Semi-HMM-based Nucleic Acid Parser: a gene prediction tool | |||||
| Snippy | NGS, SNP, variants | homepage | command line tool | SNIPPY | gwdu100, HPC |
| Rapid haploid variant calling and core genome alignment | |||||
| SnpEff | annotation, variants | homepage | command line tool | SNPEFF | Galaxy, gwdu100, HPC |
| Genomic variant annotations and functional effect prediction toolbox. | |||||
| SNPiR | NGS, SNP, analysis, variants | publication | command line tool | SNPIR-TOOL | gwdu100, HPC |
| a suite of tools for reliable identification of genomic variants using RNA-seq data | |||||
| SOAPaligner | NGS, sequence alignment | homepage | command line tool | SOAP2-ALIGNER | gwdu100, HPC |
| alignment tool | |||||
| SOAPdenovo | NGS, assembly | homepage | command line tool | SOAP2-DENOVO | gwdu100, HPC |
| de novo short reads assembler | |||||
| SOAPdenovo-Trans | NGS, assembly | homepage, publication | command line tool | SOAP-DENOVO-TRANS | gwdu100, HPC |
| A de novo transcriptome assembler designed specifically for RNA-Seq. | |||||
| SortMeRNA | NGS, filter/trimming, special purpose | homepage | command line tool | SORTMERNA | gwdu100, HPC |
| a program tool for filtering, mapping and OTU-picking NGS reads in metatranscriptomic and metagenomic data | |||||
| SPAdes | NGS, assembly | homepage, manual | command line tool | SPADES | gwdu100, HPC |
| An assembly toolkit containing various assembly pipelines. | |||||
| SRA-Toolkit | NGS, utilities | publication | command line tool | SRATOOLKIT | Galaxy, gwdu100, HPC |
| toolkit to convert .sra files into other formats | |||||
| SRST2 | special purpose | homepage | command line tool | SRST2 | gwdu100, HPC |
| Short Read Sequence Typing for Bacterial Pathogens | |||||
| SSPACE-LongRead | NGS, scaffolding | homepage, publication | command line tool | SSPACE-LONGREAD | gwdu100, HPC |
| a program for scaffolding longreads (e.g. PacBio RS reads) | |||||
| SSPACE-Standard | NGS, scaffolding | homepage, publication | command line tool | SSPACE-STANDARD | gwdu100, HPC |
| a program for scaffolding pre-assembled contigs using NGS paired-read data | |||||
| Stacks | NGS, special purpose | homepage, publication | command line tool | STACKS | gwdu100, HPC |
| software pipeline for building loci from short-read sequences | |||||
| Staden Package | NGS, analysis, assembly | homepage | graphical user interface | STADEN | gwdu100, HPC |
| tools for DNA sequence assembly, editing and sequence analysis | |||||
| STAR | NGS, sequence alignment | homepage | graphical user interface | STAR | Galaxy, gwdu100, HPC |
| Spliced Transcript Alignment to a Reference: fast RNA-seq read mapper | |||||
| Structure | phylogenetics | homepage | graphical user interface | STRUCTURE | gwdu100, HPC |
| A software package for using multi-locus genotype data to investigate population structure. | |||||
| Subread | NGS, SNP, counting, sequence alignment | homepage | command line tool | SUBREAD | Galaxy, gwdu100, HPC |
| High-performance read alignment, quantification and mutation discovery. The package contains the programs Subread, Subjunc, featureCounts, Sublong and exactSNP. | |||||
| SVDetect | NGS, variants | homepage, manual | command line tool | SVDETECT | gwdu100, HPC |
| SVDetect is a application for the isolation and the type prediction of intra- and inter-chromosomal rearrangements from paired-end/mate-pair sequencing data. | |||||
| Tabix | genomics, special purpose | homepage, publication | command line tool | TABIX | gwdu100, HPC |
| tool for fast retrieval of sequence features from generic TAB-delimited files | |||||
| Tandem Repeats Finder | genomics, special purpose | homepage | command line tool | TANDEMREPEATSFINDER | gwdu100, HPC |
| a program to locate and display tandem repeats in DNA sequences | |||||
| T-Coffee | multiple sequence alignment, sequence alignment | homepage | command line tool | TCOFFEE | gwdu100, HPC |
| a multiple sequence alignment program. Its main characteristic is that it will allow you to combine results obtained with several alignment methods | |||||
| Tomahawk | special purpose | homepage | command line tool | TOMAHAWK | gwdu100, HPC |
| Fast calculations of linkage-disequilibrium in large-scale human cohorts | |||||
| TopHat | NGS, sequence alignment | homepage | command line tool | TOPHAT | Galaxy, gwdu100, HPC |
| fast splice junction mapper for RNA-Seq reads that aligns RNA-Seq reads to mammalian-sized genomes using Bowtie | |||||
| Trans-ABySS | NGS, assembly | homepage, publication | command line tool | TRANSABYSS | HPC |
| de novo assemly of RNA-Seq data | |||||
| Transrate | NGS, assembly, quality control | homepage | command line tool | TRANSRATE | gwdu100 |
| software for de-novo transcriptome assembly quality analysis | |||||
| Trim Galore! | NGS, filter/trimming, quality control | homepage | command line tool | TRIMGALORE | gwdu100, HPC |
| wrapper tool around Cutadapt and FastGC to consistently apply quality and adapter trimming to FastQ files | |||||
| Trimmomatic | NGS, filter/trimming | homepage | command line tool | TRIMMOMATIC | Galaxy, gwdu100, HPC |
| flexible trimmer for Illumina NGS data | |||||
| TRINITY | NGS, assembly | homepage, publication | command line tool | TRINITY | Galaxy, gwdu100, HPC |
| de novo reconstruction of transcriptomes from RNA-Seq data | |||||
| tRNAscan_SE | genomics, special purpose | homepage, publication | command line tool | TRNASCAN-SE | gwdu100, HPC |
| a program for improved detection of transfer RNA genes in genomic sequence | |||||
| UCSC | genome browser, genomics | homepage | command line tool | UCSC | gwdu100, HPC |
| genome browser | |||||
| Velvet | NGS, assembly | homepage | command line tool | VELVET | gwdu100, HPC |
| sequence assembler for very short reads | |||||
| VEP | SNP, variants | homepage | command line tool | VEP | gwdu100, HPC |
| Variant Effect Predictor predicts the functional effects of genomic variants. | |||||
| Vienna RNA package | structural biology | homepage | command line tool | VIENNA-RNA | gwdu100, HPC |
| C code library and several stand-alone programs for the prediction and comparison of RNA secondary structures | |||||
| Vlion | electron microscopy | homepage, tutorial | graphical user interface | VLION | HPC |
| A slightly vectorized (AVX & SSE instructions) version of the original RELION 1.4 code. | |||||
| wtdbg2 | NGS, assembly, nanopore sequencing, sequence alignment | homepage | command line tool | WTDBG2 | gwdu100, HPC |
| A de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies. | |||||
last modified: 14.05.2020 - 11:04